The Importance of Antiretroviral Manufacturing

By: Tarun Agarwal


The use of antiretroviral drugs (ARVs) is vital in the management of HIV/AIDS. Aurobindo Pharma aims to achieve a wider access to HIV treatment, care and support through ARV manufacturing.

According to an UNAIDS report, some 60 million people worldwide have been infected since the start of the pandemic, with over 25 million deaths, and 14 million orphaned children in Southern Africa alone. Half of the patients affected with HIV/AIDS are in urgent need of treatment and majority of them belong to resource limited countries.

Antiretroviral treatment reduces both the deaths and new infections from HIV/AIDS, but these drugs are expensive and the medications are not available in all countries. The World Health Organization (WHO) recommends early start of anti-retroviral therapy as the key to HIV prevention strategy.

To ensure that treatment is available within reach in developing countries, Aurobindo Pharma has ensured expansion of its global footprint in providing quality medicines at affordable prices. With continuous quality improvement efforts, the company has reduced the cost of treatment to less than 1/10th of the innovators products, thereby treating over seven million patients of which an estimated four million are children.

Who is Aurobindo?
A leading pharmaceutical manufacturing company, Aurobindo Pharma is headquartered at Hyderabad, India. The company which commenced operations with a single unit manufacturing Semi-Synthetic Penicillin (SSP), has now evolved into a knowledge driven company that manufacturing active pharmaceutical ingredients and formulation products.

Aurobindo Pharma is R&D focused and has a multi-product portfolio with manufacturing facilities in several countries. They are also one of the few companies to be present across the beta-lactam and non-beta-lactam segments.

Why Aurobindo?
• Highest number of paediatric formulations to meet the global need for HIV therapy
• Well-integrated supply chain management for ARV supplies to over 100 countries
• Over 1100 ARV filings across the globe
• Medical education programs conducted regularly to ensure healthcare providers are informed about the proper use of Aurobindo’s medicines for HIV/AIDS

Aurobindo has actively partnered with various international organizations such as PSCMS, UNICEF, Clinton Foundation, IDA, MSF, Crown, PAHO, several health ministries, private distributors and institutions.

The pharma company is also partnering with the Medicines Patent Pool Foundation to make generic versions of ARV medicines widely available. They work closely with various funding agencies like USAID, PEPFAR, Global fund, Unitaid, World Bank and many other international bodies.

Aurobindo Worldwide
Aurobindo Pharma has a global presence across 100 countries including key players such as China, Brazil, Japan, Netherlands, South Africa, Thailand, UK, USA and Russia. In India, Aurobindo has three dedicated research centres, making it one of the largest R&D facilities in the country.

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Tarun Agarwal is a blogger with a gold medal in Chemistry. He continues to write about the latest developments in the world of medicine. He also shares his thoughts on the same by applying his knowledge in creating or modifying formulae.

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