Androgenetic alopecia among men or male pattern baldness is quite prevalent. When a person has this condition, hair loss begins as early because the age of twenty. Generally, the onset of baldness would possibly come even during the patient's teenage years. Hair loss typically begins with receding hair lines. As such, the frontal hair line becomes higher. Additionally to that, hair shedding becomes excessive and the hair at the rear portion of the head becomes thinner. Based on some researches, the one that just inherited the hair loss condition would possibly suffer either a bigger or lesser hair loss. Sadly, there was no economical cure for an androgenetic hair loss condition. Scientists noted that continuous research on the reason for hair loss condition should be made.
In pursuance to the goal of devising a cure for hereditary hair loss conditions, many studies are made in order to identify the particular gene which is involved within the occurrence of hair loss. Fortunately, a recent study has reaped significant results. Researchers headed by Professor Markus N?then of the Life & Brain Centre of the Bonn University Clinic and Dr. Roland Kruse of the Skin Clinic of D?sseldorf University Clinic announced that they need discovered one among the genetic factors that are responsible for hair loss.
Background of the Study...
Researchers conducted a study among several men which had androgenetic alopecia. The criterion was that alopecia should run in the family. As such, several male members of the family should be experiencing hair loss throughout the study period. After the researchers were chosen, blood samples were taken from the respondents. The researchers then used the blood samples so as to look for "candidate genes". In their initial step, they successfully identified a series of chromosomes that might be the culprit for hair loss. Professor N?then points out that "one variant of this gene was found among men who suffered from premature balding at a very early stage."
Axel Hilmer, one amongst the researchers says that the genetic variant that promotes hair loss might be caused by the presence of high levels of androgen receptors in the scalp. He explains that based mostly on the study findings, "Either additional androgen receptors are formed among the boys affected, or the variant of the receptor which develops as a result of the genetic change is additional stable and isn't lessened thus quickly." Such occurrences may account for the increased amount of androgens, that in flip promotes hair loss.
Researchers say that the findings of the study showed not only why hair loss probably happens. Rather, it also explains how hair loss is inherited. They found that the gene that is an androgen receptor lies on the X chromosomes. Based mostly on initial studies, the X chromosome of males is usually inherited from the mother. As such, the study implies that men sometimes take on hereditary characteristics from their grandfather on their mother's side.
However, researchers conjointly noticed that hair loss conditions are not only caused by just one gene. Rather, they stress out that their studies show that there are other genes that may be involved. These genes are independent of the gender of the patient. Thus, hair loss would possibly also be inherited directly from a father to a son.
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